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. 2024 Nov 5;6(6):893–903. doi: 10.1016/j.jaccao.2024.08.008

Table 2.

Cause-Specific Hazards Regression Models for Cancer Death, Non–Breast Cancer Malignancy, and New Chemotherapy

Exposure Cancer Death
Non–Breast Cancer Malignancy
New Chemotherapy
HR (95% CI) P Value E Value HR (95% CI) P Value E Value HR (95% CI) P Value E Value
Incident MI/HF 3.94 (3.38-4.59) <0.001 7.34 1.39 (1.06-1.82) 0.016 2.13 1.25 (1.02-1.53) 0.029 1.61
Incident MI 2.14 (1.32-3.45) 0.002 3.7 1.42 (0.91-2.21) 0.12 0.99 (0.74-1.31) 0.93
Incident HF 4.50 (3.84-5.29) <0.001 8.47 1.60 (1.32-1.92) <0.001 2.58 1.21 (1.08-1.37) 0.002 1.54
Incident MI and HF 1.79 (0.80-4.00) 0.15 0.70 (0.31-1.56) 0.38 0.94 (0.60-1.47) 0.77

Covariates in all models include age, neighborhood income quintile, rural residence, Charlson Comorbidity Index, chemotherapy, radiotherapy, trastuzumab, left-sided breast cancer, diabetes, hypertension, breast cancer stage at diagnosis, year of cohort entry, chronic obstructive pulmonary disease, and chronic kidney disease.

Abbreviations as in Table 1.