Figure 1.

Flowchart of Participation in the HARMOny Study

The colors represent the 3 different statistical comparisons made: blue illustrates coronary artery calcium (CAC) scores of the HARMOny (Health After eaRly Menopause Due to Oophorectomy) premenopausal risk-reducing salpingo-oophorectomy (RRSO) group vs the postmenopausal RRSO group (aged 60-70 years at the study visit); grey shows CAC scores of the HARMOny early premenopausal RRSO group (age ≤41 years) vs the late premenopausal RRSO group (age 41-45 years); and pink compares CAC scores of the premenopausal RRSO group from HARMOny eligible for the ROBINSCA (Risk or Benefit in Screening for Cardiovascular Disease) cohort vs the ROBINSCA external reference cohort (aged 55-70 years at the study visit). This latter comparison is indicated by a dashed line.