Table 3.
Urodynamic and urinary diary data before and after surgery in women allocated tension-free vaginal tape procedure or colposuspension. Values are medians (interquartile ranges) unless stated otherwise
| Vaginal tape group
|
Colposuspension group
|
P value*
|
||||
|---|---|---|---|---|---|---|
| Before surgery
|
6 months postoperatively
|
Before surgery
|
6 months postoperatively
|
|||
| Cystometry: | (n=175) | (n=159) | (n=169) | (n=134) | ||
| Volume at first desire to void (ml) | 194 (140-270) | 236 (146-298) | 189 (139-249) | 217 (172-289) | 0.71 | |
| Cystometric capacity (ml) | 461 (407-503) | 450 (400-500) | 450 (396-500) | 443 (400-502) | 0.39 | |
| Maximum flow rate (ml/s) | 25 (19-33) | 20 (15-25) | 24 (18-34) | 20 (14-26) | 0.38 | |
| Maximum voiding pressure (cm H2O) | 28 (15-38) | 30 (20-38) | 25 (18-38) | 30 (20-40) | 0.63 | |
| Post micturition residual (ml) | 0 | 0 (0-50) | 0 (0-7) | 0 (0-35) | 0.59 | |
| No (%) with voiding disorder† | 1 (1) | 11 (9) | 0 | 8 (7) | 0.76 | |
| No (%) with genuine stress incontinence‡ | 175 (100) | 17 (11) | 169 (100) | 20 (15) | ||
| No (%) with unstable detrusor contractions (with or without symptoms)‡ | 2 (1) | 12 (8) | 2 (1) | 13 (10) | 0.58 | |
| Urethral pressure profilometry: | (n=81) | (n=82) | (n=70) | (n=71) | ||
| Functional urethral length at rest (mm) | 29 (26-37) | 30 (24-34) | 29 (27-33) | 34 (30-37) | 0.07 | |
| Maximum urethral closure pressure at rest (mm) | 45 (27-56) | 37 (26-52) | 51 (31-60) | 46 (38-37) | 0.085 | |
| Functional urethral length at cough (mm) | 0 (0-21) | 20 (17-26) | 0 (0-13) | 25 (20-29) | 0.12 | |
| Maximum urethral closure pressure at cough (mm) | 0 (0-15) | 45 (32-60) | 0 (0-19) | 52 (34-87) | 0.24 | |
| Pressure transmission ratio (%): | ||||||
| 1st quarter | 86 (80-93) | 100 (90-100) | 91 (86-100) | 110 (100-118) | 0.48 | |
| 2nd quarter | 80 (75-86) | 105 (100-118) | 78 (75-82) | 113 (100-140) | 0.56 | |
| 3rd quarter | 57 (44-64) | 93 (68-107) | 60 (52-71) | 85 (65-114) | 0.77 | |
| 4th quarter | 19 (10-28) | 29 (18-43) | 30 (13-35) | 38 (24-44) | 0.67 | |
| 1 hour perineal pad test: | (n=170) | (n=150) | (n=157) | (n=128) | ||
| Change in pad weight (g) | 18 (6-36) | 0 (0-0.2) | 16 (6-38) | 0 (0-0.3) | 0.83 | |
| No (%) with weight change <1g | 4 (2) | 128 (73) | 5 (3) | 109 (65) | ||
| Frequency volume data: | (n=113) | (n=76) | (n=99) | (n=47) | ||
| Voided volume per 24 hours (ml) | 1739 (1400-2187) | 1824 (1383-2133) | 1714 (1407-2088) | 1696 (1375-2048) | 0.77 | |
| Average voided volume (ml) | 221 (180-274) | 262 (216-319) | 237 (164-286) | 232 (187-304) | 0.15 | |
| Micturition over 24 hours | 8 (6-10) | 7 (5-8) | 7 (6-10) | 7 (6-8) | 0.073 | |
| Episodes of nocturia | 1 (0-1) | 1 (0-1) | 1 (0-1) | 1 (0-1) | 0.022 | |
| Leaks over 24 hours§ | 3 (1-5) | 0 | 2 (1-4) | 0 | 0.67 | |
*
Wilcoxon rank sum test, comparing change from baseline to review between two groups.
†
Two out of three of peak flow <15 ml/s, maximum voiding pressure >50 cm H2O, and residual volume >100ml, given as percentage of patients with complete postoperative voiding data (n=121 for vaginal tape, n=110 for colposuspension).
‡
Percentage of patients undergoing repeat investigation (n=159 for vaginal tape, n=134 for colposuspension).
§
Significant reduction in leakage episodes after surgery in both groups (P<0.0001, Wilcoxon matched pairs test).