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. 2024 Dec 12;30:101402. doi: 10.1016/j.mtbio.2024.101402

Fig. 6.

Fig. 6

Evaluation of extracellular matrix remodeling in mildly elastase-treated decellularized tissue-engineered vascular grafts in the rat arteriovenous graft models. A) Masson's trichrome staining of dTEVGs with or without mild elastase treatment at day 42 (scale bar, 50 μm). B) The collagen area proportion of dTEVGs with or without mild elastase treatment at day 42 (n = 3). C) Herovici's staining of dTEVGs with or without mild elastase treatment at day 42, mature collagen indicated by yellow arrows (scale bar, 50 μm). D) Picrosirius red staining of dTEVGs with or without mild elastase treatment at day 42 (scale bar, 50 μm). E) The immunofluorescence staining of collagen Ⅰ and Ⅲ at day 42 between dTEVGs with or without mild elastase treatment (scale bar, 50 μm). F) The positive area proportion of collagen Ⅰ and Ⅲ at day 42 in dTEVGs with or without mild elastase treatment (n = 4). The dotted line showing the structure of the grafts. Col Ⅰ: collagen Ⅰ. Col Ⅲ: collagen Ⅲ. Data are represented as mean ± standard deviations. ∗P < 0.05, ∗∗P < 0.01, ∗∗∗P < 0.001, ∗∗∗∗P < 0.0001.