Appendix 1.
Frequency of other mutant alleles of the pfcrt gene in blood
| Blood (N=74) | ||||
|---|---|---|---|---|
| Codons | Strains and mutations observed | Numbers | Proportions (%) | |
| Blood (n=59) | ||||
| Crt_74 | Wild type | Met-74 | 47 | 79.66 |
| Mutants | Ile-74 | 5 | 8.47 | |
| Lys-74 | 1 | 1.69 | ||
| Leu-74 | 5 | 8.47 | ||
| Pro-74 | 0 | 0 | ||
| Trp-74 | 1 (1,69) | 1.69 | ||
| Blood (n=64) | ||||
| Crt_75 | Wild type | Asn-75 | 48 | 75.00 |
| Mutants | Glu-75 | 5 | 7.81 | |
| Lys-75 | 6 | 9.38 | ||
| Gln-75 | 0 | 0 | ||
| Tyr-75 | 5 | 7.81 | ||
| Blood (n=64) | ||||
| Crt_76 | Wild type (K) | Lys-76 | 40 | 62.50 |
| Mutants | Thr-76 | 10 | 15.63 | |
| Gly-76 | 1 | 1.56 | ||
| Ile-76 | 1 | 1.56 | ||
| Glu-76 | 12 | 18.75 | ||