Table 5.

Prevalences of haplotypes of pfcrt, pfdhfr genes.

		Allelic forms
Gene	Haplotypes	M74I	N75E	K76T	n	Prevalences
pfcrt (N* = 64)	Wild	M	N	K	40	62,5
	Simple mutants				8	12,5
		M	N	T	6	9,37
		Other			2	3,12
	Double mu-	N	Y	Q	4	6,25
	Triple mutants				12	18,75
		I	E	T	4	6,25
		L	K	Q	6	9,37
		Other			2	3,12
Gene	Haplotypes	N51I	C59R	S108N	n	Prevalences
pfdhfr (N* = 86)	Wild	N	C	S	12	13,96
	Simple mutants				9	10,47
		N	C	N	2	2,33
		Other			7	8,13
	Double mu-				26	30,23
		N	R	N	8	9,30
		I	C	N	7	8,13
		Other			11	12,79
	Triple mutants				39	45,34
		I	R	N	27	31,40
		Other			12	13,95

N* represents the total number of isolates successfully sequenced at the three sites. A capital letter in the allelic forms column represents the single-letter code for the amino acids. The amino acids resulting from the mutation of pfcrt and pfdhfr are underlined and in bold. The frequencies determined correspond to the number of observations out of the number of hits per gene. The list of other mutants can be found in Supplementary Tables (Appendix 2 for pfcrt and Appendix 4 for pfdhfr-ts).