Table 7.
Blood (N= 93) | ||||||||
---|---|---|---|---|---|---|---|---|
Haplotype | Y493H | R539T | I543T | C580Y | M476I | R561H | n | Proportion |
Wild | Y | R | I | C | M | R | 72 | 77,42 |
Simple Mutants | 7 | 7,53 | ||||||
Y | R | I | C | K | R | 1 | ||
Y | R | I | C | R | R | 1 | ||
Y | R | I | C | T | R | 1 | ||
Y | R | I | C | M | C | 1 | ||
C | R | I | C | M | R | 1 | ||
Y | R | I | G | M | R | 1 | ||
Y | R | I | S | M | R | 1 | ||
Double Mutants | 9 | 9,68 | ||||||
Y | R | I | C | G | C | 1 | ||
Y | G | I | S | M | R | 1 | ||
P | R | I | C | M | C | 1 | ||
Y | R | M | C | M | C | 1 | ||
Y | R | F | P | M | R | 1 | ||
F | T | I | C | M | R | 1 | ||
F | R | I | C | R | R | 1 | ||
Y | R | I | C | S | C | 1 | ||
Y | R | I | R | M | L | 1 | ||
Triple Mutants | 3 | 3,22 | ||||||
H | R | I | C | I | C | 1 | ||
Y | R | M | P | M | W | 1 | ||
Y | P | F | F | M | R | 1 | ||
Quadruple Mutants | 2 | 2,15 | ||||||
Y | T | S | P | M | S | 1 | ||
F | T | I | C | G | C | 1 |
A capital letter in the genotypes column represents the single-letter code for the amino acids. The amino acids resulting from the mutation are underlined and in bold. The prevalences determined correspond to the number of observations out of the number of hits per gene.