Table 4. Correlation and regression analysis of nucleotide composition of 16S rRNA and optimal growth temperature (T_opt).

	ra	Slopeb	P-value on slopec
(A) Paired regions
A	–0.891	–0.153	<0.001
C	0.931	0.192	<0.001
G	0.889	0.147	<0.001
T	–0.928	–0.187	<0.001
(B) Unpaired regions
A	–0.297	–0.017	0.051
C	0.643	0.033	<0.001
G	0.412	0.027	0.005
T	–0.657	–0.043	<0.001

^aPearson correlation coefficient.

^bThe slope of the linear regression line.

^cThe associated probability associated with the null hypothesis (regression line slope = 0).