Table 3. Resistance of 122 H.pylori strains to digestion by 14 REs, by geographic origin of the strain.
H.pylori methyltransferase | RE examined | Percent of strains resistant to the specified RE | |||||
---|---|---|---|---|---|---|---|
Asia-Pacific (n = 42) | North America (n = 22) | South America (n = 27) | Europe (n = 28) | Africa (n = 3) | Total (n = 122) | ||
M.HpyAI | NlaIII | 100 | 100 | 100 | 100 | 100 | 100 |
M.HpyAIII | MboI | 95 | 100 | 100 | 96 | 100 | 98 |
M.HpyAII | MboII | 55 | 36 | 63 | 57 | 33 | 53 |
M.HpyAIV | HinfI | 64 | 45 | 44 | 61 | 33 | 55 |
M.HpyVIII | HpaII | 76 | 68 | 67 | 54 | 67 | 67 |
M.HpyAVIB | DdeI | 60 | 36 | 22 | 57 | 0 | 45 |
M.Hpy178VI | FokI | 2 | 5 | 0 | 0 | 0 | 2 |
M.Hpy178VI | TaqI | 90 | 91 | 93 | 71 | 67 | 86 |
M.HpyV | HaeIII | 43 | 32 | 48 | 29 | 0 | 38 |
M.HpyCH4III | HpyCH4III | 50 | 73 | 30 | 50 | 100 | 51 |
M.HpyCH4IV | HpyCHIV | 76 | 77 | 81 | 61 | 67 | 74 |
M.HpyCH4V | HpyCH4V | 64 | 82 | 70 | 75 | 67 | 71 |
M.Hpy188I | Hpy188I | 21 | 23 | 22 | 14 | 67 | 21 |
M.Hpy99I | Hpy99I | 57 | 73 | 67 | 57 | 67 | 62 |
Number of resistances | Mean ± SD | 8.4 ± 1.9 | 8.3 ± 2.1 | 8.0 ± 1.6 | 8.0 ± 1.8 | 8.0 ± 1.0 | 8.2 ± 1.9 |
Range | 3–13 | 4–12 | 4–11 | 4–12 | 7–9 | 3–13 |