Figure 2.

Splicing events for generating ATF3ΔZip2a and b and comparison of their nucleotide and amino acid sequences. (A) Splicing events for generating ATF3ΔZip2a and b and their nucleotide and amino acid sequences are compared with those for full-length ATF3 and ATF3ΔZip as described in Liang et al. (33). Exon D′ is comprised of a 76 base sequence of intron C (shaded squares) that precedes exon D. Exon E′ is an original intron D of 91 bp (dotted square) and transcribed into ATF3ΔZip2a mRNA. Leucine residues in the zipper region were marked. (B) Schematic representations of the full-length ATF3, ATF3ΔZip and ATF3ΔZip2 are shown. Basic, Zip, A and R represent the basic, leucine zipper, activation, repression region, respectively (21).