Table 2. Effects of termination by addition of N-AcCys on the reaction of dGuo with HOCl^a.

Condition	DDiz (µM)	dIz (µM)	8-Cl-dGuo (µM)	dGuo (µM)
+N-AcCys	14.2 ± 3.2	6.0 ± 0.3	24.4 ± 2.3	615 ± 2
–N-AcCys	<0.1	<0.1	22.4 ± 0.5	647 ± 13

^adGuo (1 mM) was incubated with 1 mM NaOCl in 100 mM sodium phosphate buffer (pH 7.4) at 37°C for 15 min. The reaction mixture was analyzed by RP-HPLC after termination by addition of 2 mM N-AcCys (+N-AcCys) or without termination (–N-AcCys). Means ± SD (n = 3) are presented.