Table 4.
Any Grade | Grade 3–4 | |
---|---|---|
N (%) | N (%) | |
- No toxicity | 135 (55%) | 218 (89%) |
- Any toxicity | 110 (45%) | 27 (11%) |
Toxicity * | ||
- Cutaneous toxicity | 76 (31%) | 1 (<1%) |
- Hypothyroidism | 12 (5%) | 0 |
- Colitis | 10 (4%) | 4 (2%) |
- Arthritis | 9 (4%) | 1 (<1%) |
- Hepatic toxicity | 8 (3%) | 7 (3%) |
- Pneumonitis | 8 (3%) | 2 (1%) |
- Nephritis | 4 (2%) | 3 (1%) |
- Hypophysitis | 1 (<1%) | 1 (<1%) |
- Pancreatic toxicity | 1 (<1%) | 1 (<1%) |
- Adrenal insufficiency | 1 (<1%) | 1 (<1%) |
- Gastritis | 1 (<1%) | 1 (<1%) |
- Myositis | 1 (<1%) | 1 (<1%) |
- Myocarditis | 1 (<1%) | 1 (<1%) |
- Myelitis | 1 (<1%) | 1 (<1%) |
* Patients may have more than one toxicity. N: number of patients.