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. 2025 Jan 5;17(1):143. doi: 10.3390/cancers17010143

Table 4.

Immune-related adverse events (irAEs) from adjuvant anti-PD-1 therapy in patients with resected melanoma.

Any Grade Grade 3–4
N (%) N (%)
-  No toxicity 135 (55%) 218 (89%)
-  Any toxicity 110 (45%) 27 (11%)
Toxicity *
-  Cutaneous toxicity 76 (31%) 1 (<1%)
-  Hypothyroidism 12 (5%) 0
-  Colitis 10 (4%) 4 (2%)
-  Arthritis 9 (4%) 1 (<1%)
-  Hepatic toxicity 8 (3%) 7 (3%)
-  Pneumonitis 8 (3%) 2 (1%)
-  Nephritis 4 (2%) 3 (1%)
-  Hypophysitis 1 (<1%) 1 (<1%)
-  Pancreatic toxicity 1 (<1%) 1 (<1%)
-  Adrenal insufficiency 1 (<1%) 1 (<1%)
-  Gastritis 1 (<1%) 1 (<1%)
-  Myositis 1 (<1%) 1 (<1%)
-  Myocarditis 1 (<1%) 1 (<1%)
-  Myelitis 1 (<1%) 1 (<1%)

* Patients may have more than one toxicity. N: number of patients.