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. 2025 Jan 3;17(1):127. doi: 10.3390/cancers17010127

Table 2.

Cases of recurrence of G2 EEC and their characteristics.

Stage LVSI Symptoms Site Treatment Disease-Free Survival (Months) Survival After Recurrence (Months)
IA Absent Vaginal bleeding Vaginal vault + pelvic LN BSC 29 14
IA Absent Persistent cough Lungs HT 42 33
IA Absent 1st—asymptomatic (found on examination)
2nd—shortness of breath
1st—inguinal LN
2nd—ediastinal LN
1st SE
2nd BSC
57 29
IB Present Abdominal pain Lungs + LN (supraclavicular, para-aortic, pelvic) BSC 8 3
IB Present Diabetic complications + diarrhoea Paracardiac LN + peritoneum + omentum + sigmoid HT 11 10
IB Absent Persistent cough lungs + mediastinal LN + adrenal BSC 21 3
IB Absent Persistent discharge Vaginal vault Chemotherapy 3 24
IB Present Vaginal bleeding Vaginal vault + pelvic LN (recurrence as G3 ECC) Chemotherapy 23 43
IB Absent Fatigue and reduced appetite Peritoneum—malignant ascites + LN (retrocaval, paracardiac) BSC 63 8
IB Present 1st—vaginal bleeding
2nd—shortness of breath
1st—vaginal vault
2nd—lungs
1st SE
2nd CT
27 58
IB Present Asymptomatic (incidental finding on CT scan for other reason) Peritoneal nodularity and ascites (small volume disease) + umbilical nodule RT + HT 31 78
IB Present Vaginal bleeding Vaginal vault + pelvic tumour SE + HT 27 107
IIIA Present Diarrhoea Pelvic + paraaortic LN RT 18 42
IIIA Absent Pelvic pain Lungs + bones RT + HT 55 24
IIIB Present Asymptomatic (found on examination) Vaginal vault + pelvic LN HT 9 5
IIIB Present Vaginal bleeding 1st—vaginal vault
2nd—pelvic LN + bones
1st SE
2nd BSC
37 14

LN = lymph nodes; RT = radiotherapy; CT = chemotherapy; HT = hormonotherapy; BSC = best supportive care; SE = surgical excision.