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. 2024 Dec 26;26(1):87. doi: 10.3390/ijms26010087

Figure 9.

Figure 9

Metabolic pathways in starving BME26 cells: Key regulatory mechanisms in response to nutrient deprivation. Glycogen degradation is upregulated, and gluconeogenesis is activated, with PEPCK (upregulated) and PK (downregulated) playing crucial roles. Metabolite flow is directed toward the pentose phosphate pathway, and autophagy is induced, as indicated by the upregulation of ATG4, ATG6, and ATG8.