Table 3.
Cox regression analysis for overall survival and disease-free survival
| Univariate analysis | Multivariate analysis | |||
|---|---|---|---|---|
| P value | HR (95%CI) | P value | HR (95%CI) | |
| Overall survival | ||||
| Pathological complete response, pCR | 0.001 | 0.232 (0.100-0.541) | ||
| Major pathological response, MPR | < 0.001 | 0.379 (0.222–0.647) | ||
| ypT stage | < 0.001 | 1.488 (1.231–1.799) | 0.026 | 1.284 (1.030–1.600) |
| ypN stage | 0.001 | 1.582 (1.210–2.069) | ||
| ypTNM stage | < 0.001 | 1.819 (1.420–2.331) | ||
| TRG grade | < 0.001 | 1.371 (1.168–1.608) | ||
| rTN stage | < 0.001 | 1.731 (1.382–2.169) | 0.001 | 1.527 (1.186–1.966) |
| Disease free survival | ||||
| Pathological complete response, pCR | 0.001 | 0.330 (0.168–0.645) | ||
| Major pathological response, MPR | 0.001 | 0.431 (0.267–0.696) | ||
| ypT stage | < 0.001 | 1.404 (1.181–1.669) | ||
| ypN stage | 0.001 | 1.552 (1.200-2.008) | ||
| ypTNM stage | < 0.001 | 1.733 (1.381–2.174) | 0.010 | 1.677 (1.040–2.936) |
| TRG grade | < 0.001 | 1.318 (1.140–1.523) | ||
| rTN stage | < 0.001 | 1.555 (1.272–1.902) | ||