Table 2.
Logistic Regression Analysis of Hematological Parameters Associated with Sarcopenia in different categories
| Variable | Normal (Non-sarcopenic) (n = 202) | Sarcopenic Non-obese (n = 153) | Sarcopenic Obesity (n = 56) | Total Sarcopenic (n = 209) |
|---|---|---|---|---|
| Hemoglobin (per 1 g/dL decrease) | ||||
| OR (95% CI) | 1.00 (Reference) | 1.40 (1.16–1.69) | 1.48 (1.19–1.84) | 1.40 (1.22–1.61) |
| p-value | - | < 0.001 | < 0.001 | < 0.001 |
| Hematocrit (per 3% decrease) | ||||
| OR (95% CI) | 1.00 (Reference) | 1.35 (1.12–1.63) | 1.42 (1.15–1.75) | 1.35 (1.18–1.55) |
| p-value | - | 0.002 | 0.001 | < 0.001 |
| White Blood Cell Count (per 1 × 10⁹/L increase) | ||||
| OR (95% CI) | 1.00 (Reference) | 1.10 (0.98–1.24) | 1.15 (1.00-1.32) | 1.12 (1.02–1.23) |
| p-value | - | 0.103 | 0.048 | 0.018 |
| Platelet Count (per 50 × 10⁹/L decrease) | ||||
| OR (95% CI) | 1.00 (Reference) | 1.18 (0.98–1.42) | 1.22 (0.98–1.52) | 1.18 (1.02–1.37) |
| p-value | - | 0.084 | 0.078 | 0.025 |
| Red Cell Distribution Width (per 1% increase) | ||||
| OR (95% CI) | 1.00 (Reference) | 1.21 (1.07–1.37) | 1.26 (1.08–1.47) | 1.22 (1.10–1.35) |
| p-value | - | 0.003 | 0.003 | < 0.001 |
| Platelet-to-Lymphocyte Ratio (per 10-unit increase) | ||||
| OR (95% CI) | 1.00 (Reference) | 1.04 (0.98–1.10) | 1.06 (0.99–1.13) | 1.05 (0.98–1.10) |
| p-value | - | 0.172 | 0.092 | 0.051 |
OR: Odds Ratio; CI: Confidence Interval. Models are adjusted for age, sex, diabetes mellitus, cardiovascular disease, albumin, Dialysis vintage (duration of hemodialysis), Kt/V, and C-reactive protein. P < 0.05-significant, P < 0.001-highly significant