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. 2025 Jan 10;26:39. doi: 10.1186/s12891-025-08291-x

Table 2.

Logistic Regression Analysis of Hematological Parameters Associated with Sarcopenia in different categories

Variable Normal (Non-sarcopenic) (n = 202) Sarcopenic Non-obese (n = 153) Sarcopenic Obesity (n = 56) Total Sarcopenic (n = 209)
Hemoglobin (per 1 g/dL decrease)
OR (95% CI) 1.00 (Reference) 1.40 (1.16–1.69) 1.48 (1.19–1.84) 1.40 (1.22–1.61)
p-value - < 0.001 < 0.001 < 0.001
Hematocrit (per 3% decrease)
OR (95% CI) 1.00 (Reference) 1.35 (1.12–1.63) 1.42 (1.15–1.75) 1.35 (1.18–1.55)
p-value - 0.002 0.001 < 0.001
White Blood Cell Count (per 1 × 10⁹/L increase)
OR (95% CI) 1.00 (Reference) 1.10 (0.98–1.24) 1.15 (1.00-1.32) 1.12 (1.02–1.23)
p-value - 0.103 0.048 0.018
Platelet Count (per 50 × 10⁹/L decrease)
OR (95% CI) 1.00 (Reference) 1.18 (0.98–1.42) 1.22 (0.98–1.52) 1.18 (1.02–1.37)
p-value - 0.084 0.078 0.025
Red Cell Distribution Width (per 1% increase)
OR (95% CI) 1.00 (Reference) 1.21 (1.07–1.37) 1.26 (1.08–1.47) 1.22 (1.10–1.35)
p-value - 0.003 0.003 < 0.001
Platelet-to-Lymphocyte Ratio (per 10-unit increase)
OR (95% CI) 1.00 (Reference) 1.04 (0.98–1.10) 1.06 (0.99–1.13) 1.05 (0.98–1.10)
p-value - 0.172 0.092 0.051

OR: Odds Ratio; CI: Confidence Interval. Models are adjusted for age, sex, diabetes mellitus, cardiovascular disease, albumin, Dialysis vintage (duration of hemodialysis), Kt/V, and C-reactive protein. P < 0.05-significant, P < 0.001-highly significant