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. 2024 Dec 24;55(3):36. doi: 10.3892/ijmm.2024.5477

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Copyright: © 2024 Zhu et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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SWCNT-based FET device and FND-based immunosensor for MTB detection. (A) Schematic representation of SWCNTs modified by EDC/NHS and connected to Ab85B. Reproduced with permission through Creative Commons Attribution 4.0 International License from Wang J et al (79), ACS Sensors; published by American Chemical Society, 2024. (B) Schematic representation of ESAT6 (MTB critical virulence factor) detection by competitive spin-enhanced lateral flow immunoassay. Magnetically modulated fluorescence allows background-free detection. ESAT6 in the sample and test strip compete for the few Ab binding sites on the FND to accomplish competitive detection. Movement of the strip is indicated by a black arrow. Reproduced from (80), Copyright (2024), with permission through Creative Commons Attribution-NonCommercial 3.0 Unported Licence, Royal Society of Chemistry. SWCNTs, single-walled carbon nanotubes; EDC/NHS, 1-Ethyl-3-(3-dimethylaminopropyl)carbodiimide/N-Hydroxysuccinimide; ESAT6, early secreted antigenic target-6; FNDs, fluorescent nanodiamonds; TB, tuberculosis.