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. 2005 Jul 7;115(8):2149–2158. doi: 10.1172/JCI23956

Figure 4.

Figure 4

FP inhibits the activation of human T cells. Human Ob1A12 cells were activated with their target peptide MBP85–99 and MGAR B cells, and proliferation (A), IL-13 secretion (B), and IFN-γ secretion (C) were assayed. The data are presented as mean inhibitions ± SD (n = 3 or more). The uninhibited T cell proliferative responses were 2440 ± 190 cpm; the background proliferation in the absence of antigen was 85 ± 12 cpm. IFN-γ secretion was 964 ± 149 pg/ml, and IL-13 secretion was 4992 ± 352 pg/ml for activated cells not incubated with FP or CP-2G. Two independent experiments gave similar results.