Table 2. Infrared video pupillometry vs. ultrasound pupillometry in ON+ and HC eyes.
ON+ eyes (n = 52, 40 individuals) |
HC eyes (n = 100, 50 individuals) |
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Method | IVP (n = 52) | UP (n = 52) | IVP-UP (n = 52) | IVP (n = 98) | UP (n = 100) | IVP-UP (n = 98) |
PD at rest, mm, mean (SD) | 5.23 (1.11) | 4.80 (0.78) | 0.44 (0.87) | 5.55 (1.05) | 4.86 (0.85) | 0.69 (0.80) |
Correlation of IVP and UPA, r (95% CI), p | 0.56 (0.35; 0.72) p = 0.001 |
0.60 (0.47; 0.72) p = 0.001 |
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PD after direct Lstim, mm, mean (SD) | 3.33 (0.70) | 3.03 (0.70) | 0.30 (0.59) | 3.27 (0.67) | 3.01 (0.65) | 0.26 (0.52) |
Correlation of IVP and UPA, r (95% CI), p | 0.64 (0.47; 0.77) p = 0.001 |
0.63 (0.50; 0.74) p = 0.001 |
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Constriction range, %, mean (SD) | 36.0 (6.1) | 36.9 (10.4) | -0.9 (9.4) | 41.2 (4.0) | 38.0 (6.9) | 3.2 (6.4) |
CorrelationA of IVP and UP, r (95% CI), p | 0.49 (0.27; 0.66) p = 0.001 |
0.34 (0.13; 0.52) p = 0.001 |
CorrelationA = correlation coefficient calculated from marginal r2 values of linear mixed models accounting for repeated measures, HC = healthy controls, IVP = infrared video pupillometry, Lstim = light stimulus, mm = millimeters, ON+ eyes = eyes with optic neuritis, PD = pupil diameter, SD = standard deviation, UP = ultrasound pupillometry, 95% CI = 95% confidence interval.