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. 2025 Jan 10;20(1):e0315712. doi: 10.1371/journal.pone.0315712

Table 3. Demographic and clinical data of MS ON- patients with pathologic constriction ratio in UP.

Patient Sex Age (years) MS type EDSS CR, right/ left VA, right/ left pRNFLT, right/left (μm) IEAD (μm) IEPD (%)
1 male 32 RRMS 1.0 1.60/ 0.92 1.25/ 1.25 97/ 96 1 1
2 female 39 RRMS 2.5 1.31/ 0.85 1.25/ 1.25 90/ 95 5 5
3 male 49 PPMS 4.0 1.38/ 0.55 0.63/ 1.25 87/ 96 9 9
4 male 50 RRMS 2.0 1.40/ 0.71 1.25/ 1.25 89/ 94 5 5
5 female 62 RRMS 4.0 1.31/ 0.85 1.00/ 1.00 81/ 87 6 7

CR = constriction ratio, EDSS = Expanded Disability Status Scale, IEAD = intereye absolute difference, IEPD = intereye percentage difference, MS = multiple sclerosis, MS ON- = patients with multiple sclerosis without a history of ON, μm = micrometers, pRNFLT = absolute peripapillary retinal nerve fiber layer thickness, RRMS = relapsing remitting multiple sclerosis, PPMS = primary progressive multiple sclerosis, UP = ultrasound pupillometry, VA = visual acuity.