Table 4. Visual acuity in ON+ and ON- eyes.
| Study group | ON+ eyes (n = 52, 40 individuals) |
ON- eyes (n = 190, 111 individuals) |
||||
|---|---|---|---|---|---|---|
| acute ON (n = 9) | past ON (n = 43) | unaffected eyes acute ON (n = 7) | unaffected eyes past ON (n = 21) | MS ON- (n = 62) | HC (n = 100) | |
| VA, mean (SD) | 0.50 (0.33) |
0.78 (0.40) |
1.21 (0.09) |
1.06 (0.24) |
1.12 (0.20) |
1.12 (0.23) |
| Difference vs. HC (95% CI) |
-0.68 (-0.86; -0.51) |
-0.33 (-0.44; -0.22) |
-0.03 (-0.23; 0.16) |
-0.09 (-0.21; 0.03) |
-0.03 (-0.14; 0.08) |
n.a. |
| p-value, vs. HCA | <0.001 | <0.001 | 0.725 | 0.138 | 0.586 | n.a. |
Difference vs. HC = model based mean difference comparing each group to HC adjusted for age, HC = healthy controls, MS ON- = patients with multiple sclerosis without a history of ON, n.a. = not applicable, ON+/- eyes = eyes with or without optic neuritis, p-value vs. HCA = p-values based on age-adjusted linear mixed model for comparing each group with HC, SD = standard deviation, VA = visual acuity, 95% CI = 95% confidence interval.