Table 2.
Spirometrya and sputum cell counts by Chlamydia pneumoniae DNA detection status among 92 patients with chronic obstructive pulmonary disease.
| Number of Subjects | Entire Study Group | DNAb Present | DNA Absent | P-value (t-test) | |
| Age in years (SD) | 93 | 65.8 (10.7) | 66.9 (11.9) | 65.3 (10.3) | 0.53 |
| Smoking pack-years (SD) | 93 | 43.1 (25.1) | 48.9 (29.3) | 41.8 (24.1) | 0.22 |
| FEV1c (SD), L | 93 | 1.35 (0.61) | 1.34 (0.64) | 1.36 (0.61) | 0.88 |
| FEV1 % predicted (SD) | 93 | 46.9 (16.8) | 44.3 (15.1) | 48.0 (17.5) | 0.33 |
| FEV1/VCd % (SD) | 93 | 45.7 (15.4) | 42.6 (15.8) | 47.0 (15.2) | 0.22 |
| Total cell count, 106/g (SD) | 73 | 10.9 (15.4) | 9.9 (12.5) | 11.4 (16.8) | 0.70 |
| Viability, % (SD) | 73 | 61.5 (24.2) | 60.4 (22.7) | 62.0 (25.0) | 0.79 |
| Squamous Epithelial, % (SD) | 73 | 3.8 (8.6) | 3.7 (5.3) | 3.9 (10.0) | 0.92 |
| Neutrophils, % (SD) | 73 | 63.6 (25.3) | 60.6 (27.2) | 65.2 (24.5) | 0.46 |
| Macrophages, % (SD) | 73 | 25.6 (19.2) | 26.4 (21.2) | 25.2 (18.3) | 0.78 |
| Eosinophils, median % (Inter-quartile range)e | 73 | 1.2 (3.0) | 1.2 (3.7) | 1.0 (2.9) | 0.71e |
aAll spirometry after inhalation of 200 μg salbutamol. bC. pneumoniae DNA detected in peripheral blood mononuclear cells or induced sputum by nested polymerase chain reaction [14]. cFEV1: forced expiratory volume in 1 second. dVC: vital capacity. eComparison by Mann Whitney U test (SPSS).