Figure 2.

UBE2G2 inhibits UM cell metastasis and vasculogenic mimicry (VM) induced by hypoxia in vitro. (A, B) Transwell assays were performed to evaluate the migration and invasion abilities of UM cells. (C, D) Wound healing assays were used to assess cell migration ability. (E, F) Matrigel tube formation was performed to evaluate the vasculogenic mimicry abilities of UM cells. (G, H) The mRNA and protein level of VE-cadherin (a marker of VM) were used to assess cell vasculogenic mimicry ability. All data are presented as the mean ± SD of three independent experiments. ∗P < 0.05, ∗∗P < 0.01, ∗∗∗P < 0.001.