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. 2025 Jan 8;19:111–128. doi: 10.2147/DDDT.S478692

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© 2025 Duan et al.

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Effect of LY294002 on the antioxidant effect of remimazolam in brain ischemia/reperfusion (I/R) injury. (A) Flow cytometry to detect the reactive oxygen species (ROS) content of SY5Y cells in each group. (B) Relative intensity of ROS fluorescence. Relative contents of malondialdehyde (MDA) (C), superoxide dismutase (SOD) (D) and glutathione peroxidase (GSH-Px) (E) of SY5Y cells in each group. n=3. (F) Flow cytometry detection of ROS content in the brain tissues. (G) Relative intensity of ROS fluorescence. Relative contents of MDA (H), SOD (I) and GSH-Px (J) in the cerebral ischemic penumbra region of rats. n=3. *P<0.05, **P<0.01, ***P<0.001.