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. 2024 Feb 17;46(Suppl 6):S79–S85. doi: 10.1016/j.htct.2023.12.007

Table 3.

Preparation of T315I series in DNA mutation abundance testing.

Mutation abundance (Mutation/wild copies/μL) Input serial DNA mutation abundance (μL)
29.20%* 10% 5% 1% 0.1% 0%#
10% (497/4470) 15 25
5% (255/4836) 10 42
1% (52/5142) 5 43
0.50% (26/5181) 5 44
0.10% (5/5212) 5 45
0.02% (1/5218) 5 20

T315I BCR::ABL mutation (1327 copies/μL) - wild BCR::ABL (3217 copies/μL).

#

wild BCR::ABL DNA sample (5220 copies/μL).