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. 1976 Feb 15;154(2):311–318. doi: 10.1042/bj1540311

An unusual precursor of 50S ribosomes in a mutant of Escherichia coli.

F Markey, D G Wild
PMCID: PMC1172712  PMID: 779766

Abstract

Escherichia coli strain 15-28 is a mutant with a defect in ribosome synthesis that leads to the accumulation of large amounts of ribonucleoprotein ("47S") particles during exponential growth. These particles are precursors to 50S ribosomes, but are distinct from precursors detected by pulse-labelling of the parent strain and also from ribosome precursors that accumulate during inhibition of growth by CoC12. Either ribosome assembly in the mutant differs from that in the wild-type strain, or 47S particles represent a hitherto unstudied stage in the synthesis of 50S ribosomes.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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