AAV |
Adeno-Associated Virus |
Aβ |
Amyloid Beta |
Aβ40 |
Amyloid Beta 40 Peptide |
Aβ42 |
Amyloid Beta 42 Peptide |
AD |
Alzheimer’s Disease |
APP |
Amyloid Precursor Protein |
BBB |
Blood-Brain Barrier |
BDNF |
Brain-Derived Neurotrophic Factor |
BACE1 |
Beta-Site APP-Cleaving Enzyme 1 |
CAR-T |
Chimeric Antigen Receptor T-Cell Therapy |
CCL |
C-C Motif Chemokine Ligand |
CD47 |
Cluster of Differentiation 47 |
CNS |
Central Nervous System |
CRISPR |
Clustered Regularly Interspaced Short Palindromic Repeats |
CRISPR/Cas9 |
CRISPR-Associated Protein 9 System |
CRP |
C-Reactive Protein |
CXCL |
C-X-C Motif Chemokine Ligand |
DC |
Dendritic Cell |
EGFRvIII |
Epidermal Growth Factor Receptor Variant III |
FUS |
Focused Ultrasound |
GDNF |
Glial Cell Line-Derived Neurotrophic Factor |
GFAP |
Glial Fibrillary Acidic Protein |
HDAC |
Histone Deacetylase |
IFN |
Interferon |
IL |
Interleukin |
iPSC |
Induced Pluripotent Stem Cell |
JAK |
Janus Kinase |
LMTX |
Tau Aggregation Inhibitor |
LRR |
Leucine-Rich Repeat |
MCP-1 |
Monocyte Chemoattractant Protein-1 |
MDSCs |
Myeloid-Derived Suppressor Cells |
MMP |
Matrix Metalloproteinase |
MOG |
Myelin Oligodendrocyte Glycoprotein |
MSC |
Mesenchymal Stem Cell |
MS |
Multiple Sclerosis |
NAA |
N-Acetylaspartate |
NETs |
Neutrophil Extracellular Traps |
NF-κB |
Nuclear Factor Kappa-Light-Chain-Enhancer of Activated B Cells |
NfL |
Neurofilament Light Chain |
NLRP |
NOD-Like Receptor Protein |
NLRP3 |
NOD, LRR,, and Pyrin Domain-Containing Protein 3 |
NOD |
Nucleotide-Binding Oligomerization Domain |
OPCs |
Oligodendrocyte precursor cells |
PD |
Parkinson’s Disease |
PD01A |
Parkinson’s Disease Vaccine Candidate Targeting Alpha-Synuclein |
PD-1 |
Programmed Death-1 |
PD-L1 |
Programmed Death-Ligand 1 |
PET |
Positron Emission Tomography |
PLGA |
Poly(Lactic-Co-Glycolic Acid) |
p-tau |
Phosphorylated Tau |
RNA |
Ribonucleic Acid |
RNAi |
RNA Interference |
ROS |
Reactive Oxygen Species |
S1P |
Sphingosine-1-Phosphate |
SCFA |
Short-Chain Fatty Acids |
SIDS |
Stroke-Induced Immunodepression Syndrome |
SOCS |
Suppressor of Cytokine Signaling |
STAT |
Signal Transducer and Activator of Transcription |
TAMs |
Tumor-Associated Macrophages |
TGF-β |
Transforming Growth Factor-Beta |
TLR |
Toll-Like Receptor |
TMS |
Transcranial Magnetic Stimulation |
TREM2 |
Triggering Receptor Expressed on Myeloid Cells 2 |
TNF-α |
Tumor Necrosis Factor-Alpha |
VEGF |
Vascular Endothelial Growth Factor |
YKL-40 |
Chitinase-3-Like Protein 1 |