Table 4.
Summary of the effect of an ARNI in patients with an LVAD.
| Study | EF | CI | LVEDD | LVESD | BNP | MAP | NYHA Class | MPAP | Cr | CRP | GFR | Sodium | Potas-sium | BUN | BMI | Diuretic Dose |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Alishetti et al., 2020 [13] |
- | - | - | - | ↓ | ↔ | - | - | ↔ | ↔ | - | - | ↔ | ↔ | - | - |
| Sharma et al., 2020 [16] |
- | - | - | - | - | ↓ | - | - | ↔ | - | ↔ | - | ↔ | - | - | - |
| Zorz et al., 2020 [17] | - | - | ↔ | - | ↓ | ↔ | - | - | ↔ | - | - | - | - | - | - | - |
| Randhawa et al., 2020 [9] |
- | - | - | - | ↔ | ↓ | - | - | ↔ | - | - | - | ↔ | - | - | ↔ |
| Goldberg et al., 2021 [8] | - | - | ↓ | - | - | ↓ | ↓ | - | ↔ | - | - | ↔ | ↔ | ↔ | - | ↔ |
| Schnettler et al., 2021 [15] |
- | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - |
| Rawlley et al., 2023 [14] |
↔ | - | - | - | - | ↔ | - | - | - | - | - | - | - | - | ↔ | - |
Abbreviations: BMI, body mass index; BNP, brain natriuretic peptide; BUN, blood urea nitrogen; CI, cardiac index; Cr, creatinine; CRP, C-reactive protein; EF, ejection fraction; GFR, glomerular filtration rate; LVEDD, left ventricular end-diastolic diameter; LVESD, left ventricular end-systolic diameter; MAP, mean arterial pressure; MPAP, mean pulmonary arterial pressure; NYHA class, New York Heart Association Class; ↓, decreased; ↔, unchanged.