Abbreviation	Full Term
BP	Biological processes
CC	Cellular components
CH-RLSq	Cambridge-Hopkins Restless Legs Syndrome questionnaire
eQTL	Expression quantitative trait locus
FDR	False discovery rate
GO	Gene Ontology
GWAS	Genome-wide association study
HEIDI	Heterogeneity in dependent instruments
IRLSSG	International Restless Legs Syndrome Study Group
IVW	Inverse variance weighted
KEGG	Kyoto Encyclopedia of Genes and Genomes
LD	Linkage disequilibrium
MF	Molecular functions
MR	Mendelian randomization
MR-PheWAS	Phenome-wide MR analysis
NKA	Na+-K+-ATPase
PP	Posterior probabilities
pQTL	Protein quantitative trait locus
RLS	Restless legs syndrome
SMR	Summary-based Mendelian randomization
SNPs	Single nucleotide polymorphisms
STROBE-MR	Strengthening the Reporting of Observational Studies in Epidemiology–Mendelian randomization
UKB-PPP	UK Biobank plasma proteomic project