Table 4.

Treatment-emergent adverse events

Adverse event	Grade 1-2	Grade 3	Grade 4
Hematologic events
Thrombocytopenia	2 (6.9)	0	1 (3.4)
Neutropenia	1 (3.4)	0	0
Anemia	4 (13.8)	0	0
Gastrointestinal events
Diarrhea	3 (10.3)	1 (3.4)	0
Nausea	4 (13.8)	0	0
Neurologic events
Peripheral neuropathy	6 (20.7)	0	0
Seizure	1 (3.4)	0	0
Infections
Pneumonia	0	1 (3.4)	0
Eye infection	2 (6.9)	0	0
Skin infection	0	1 (3.4)	0
Upper respiratory tract infection	3 (10.3)	0	0
Other conditions
Fatigue	5 (17.2)	0	0
Skin rash	5 (17.2)	0	0
Pyrexia	4 (13.8)	0	0
Elevated aminotransferase	2 (6.9)	0	0
Hypertension	2 (6.9)	0	0

Values are presented as number (%).