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. 2024 Dec 12;36(1):102423. doi: 10.1016/j.omtn.2024.102423

Figure 2.

Figure 2

IF delivery of Cre-recombinase LNP to stably induce reporter expression

(A) Graphical representation highlighting the IF injection procedure for delivering LNP directly into the BM. (B and C) Widefield transmitted (B) and fluorescence (C) images of whole BM taken from Ai14 mice after IF LNPCre delivery. (D–H) FACS analysis of cells from IF- or IV-treated spleens (D) or femurs (E–H) comparing positivity rates between mice treated either IF or IV with LNPCre (p < 0.05).