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Effect of farnesyltransferase inhibitor I (FTI) on the radiation-induced maximum increase in binding of nuclear extracts to transcription factor consensus sequences. Cells were treated with 50 μM FTI for 18 h before irradiation, and drug was present until protein extraction. Otherwise, the protocol is the same as described in the legend of Figure 2. Fold-changes represent the mean of three independent experiments.
