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. 2025 Jan 13;8(1):e2454253. doi: 10.1001/jamanetworkopen.2024.54253

Table 1. Health-Related Quality-of-Life Scores.

HRQOL score ADT plus AAP APA alone AAP plus APA
Baseline HRQOL score, mean (SD)
Physical well-being 23.9 (5.1) 23.4 (5.0) 23.9 (4.0)
Functional well-being 19.6 (5.9) 19.2 (6.1) 18.8 (6.1)
Social well-being 21.4 (6.1) 21.4 (6.0) 20.6 (5.8)
Emotional well-being 19.7 (3.8) 18.6 (4.9) 19.2 (4.0)
Prostate cancer subscale 34.0 (8.7) 33.7 (7.1) 33.0 (6.1)
FACT-G total score 84.3 (17.2) 82.6 (17.9) 82.4 (13.7)
FACT-P total score 118.5 (24.3) 116.1 (23.9) 114.9 (18.1)
Week 25 HRQOL score, mean (SD)
Physical well-being 24.5 (4.2) 23.6 (4.9) 23.2 (5.0)
Functional well-being 19.7 (5.7) 19.5 (4.4) 20.4 (5.1)
Social well-being 20.8 (5.2) 20.9 (4.9) 20.9 (4.0)
Emotional well-being 20.7 (4.3) 19.9 (2.5) 20.7 (3.5)
Prostate cancer subscale 36.2 (6.1) 35.3 (5.8) 34.4 (6.9)
FACT-G total score 86.1 (15.8) 84.1 (12.4) 85.4 (14.6)
FACT-P total score 122.3 (20.4) 119.5 (16.4) 119.9 (20.3)

Abbreviations: AAP, abiraterone acetate plus prednisone; ADT, androgen deprivation therapy; APA, apalutamide; FACT-G, Functional Assessment of Cancer Therapy–General; FACT-P, Functional Assessment of Cancer Therapy–Prostate; HRQOL, health-related quality of life.