Table 1.

Inclusion and exclusion criteria

Inclusion criteria

Chronic coronary artery disease (CAD)

Evidence of ischemia in MIBI-SPECT examination

Coronary angiogram in the last 3 months

Angina pectoris, CCS III-IV

Optimal medical treatment (Beta-blocker, ACE-inhibitor or AT1-antagonist, Ca2+-antagonist, ASS, CSE-inhibitor, long-acting nitrate [LAN])

Not suitable for percutaneous coronary intervention (PCI) or aortocoronary bypass surgery (CABG) after discussion with a team of specialists (cardiologists and heart surgeons)

Exclusion criteria

Myocardial infarction or unstable in the last 3 months

Pacemaker with unipolar electrode

Relevant valvular heart disease

Symptomatic heart failure > NYHA II

Left ventricular ejection fraction (LVEF) < 40%