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Stability of osimertinib (n = 6)
| Prerequisite | LQC (3 ng/mL) | HQC (240 ng/mL) | |||||
|---|---|---|---|---|---|---|---|
|
|
|
||||||
| RSD% | RE% | Mean | RSD% | RE% | Mean | ||
| Plasma placed for 6 h | 25°C | 2.76 | 12.40 | -7.89 | 237.00 | 9.28 | -1.12 |
| Plasma placed for 30 days | -80°C | 2.91 | 10.30 | -2.73 | 253.00 | 6.77 | 5.63 |
| Plasma freeze-thaw cycle (×4) | -80°C | 2.97 | 4.91 | -1.12 | 264.00 | 4.53 | 10.30 |
HQC, high-quality control; LQC, low-quality control; RE, relative error; RSD, relative standard deviation.
