Table 3.
Associations between CAD severity and risk factors in patients with hypertension
| Variables | Multi-vessel coronary artery disease | |||
|---|---|---|---|---|
| β | OR | 95% CI | P value | |
| Age | 0.003 | 1.003 | 0.994 | 0.506 |
| Gender | ||||
| Female | Reference | |||
| Male | 0.519 | 1.680 | 1.372–2.056 | < 0.001 |
| BMI | 0.182 | 1.200 | 1.156–1.246 | < 0.001 |
| SBP | 0.003 | 1.003 | 0.998–1.008 | 0.188 |
| DBP | 0.002 | 1.002 | 0.993–1.010 | 0.686 |
| H-type hypertension | ||||
| No | Reference | |||
| Yes | 0.240 | 1.271 | 1.036–1.559 | 0.021 |
| Drinking | ||||
| No | Reference | |||
| Yes | − 0.117 | 0.890 | 0.635–1.246 | 0.496 |
| Somking | ||||
| No | Reference | |||
| Yes | 0.456 | 1.578 | 1.271–1.958 | < 0.001 |
| Glucose metabolism state | ||||
| NGR | Reference | |||
| Pre-DM | − 0.021 | 0.980 | 0.763–1.257 | 0.087 |
| DM | 0.517 | 1.677 | 1.299–2.164 | < 0.001 |
| TC | 0.143 | 1.154 | 1.059–1.257 | 0.001 |
| TG | 0.211 | 1.235 | 1.145–1.332 | < 0.001 |
| LDL-C | 0.220 | 1.245 | 1.109–1.399 | < 0.001 |
| FPG | 0.163 | 1.177 | 1.134–1.222 | < 0.001 |
| HbA1c | 0.196 | 1.216 | 1.125–1.315 | < 0.001 |
| TyG-BMI index | 0.022 | 1.022 | 1.018–1.025 | < 0.001 |
| Tertiles TyG-BMI index | ||||
| T1 | Reference | |||
| T2 | 0.784 | 2.190 | 1.695–2.829 | < 0.001 |
| T3 | 1.619 | 5.049 | 3.873–6.582 | < 0.001 |
Compared with single-vessel CAD
OR: odds ratios; CI: confidence interval; β: regression coefficient; SBP: systolic blood pressure; DBP: diastolic blood pressure; TyG-BMI: Triglyceride glucose index–body mass index; TC: total cholesterol; TG: triglycerides; LDL-C: low-density lipoprotein cholesterol; FPG: fasting plasma glucose; HbA1c: glycated haemoglobin; NGR: normal glucose regulation; Pre-DM: pre-diabetes; DM: diabetes mellitus