Table 1.
Characteristics of the 1,441 Parous Women
| N (%) or mean (standard deviation) | No HDP N=1,127 | Gestational hypertension N=112 | Preeclampsia N=202 | p-value |
|---|---|---|---|---|
|
| ||||
| Baseline | ||||
| Black | 564 (50) | 68 (60.7)† | 115 (56.9) | 0.029 |
| Married/live with a partner | 321 (28.5) | 33 (29.5) | 60 (29.9) | 0.91 |
| APOE ε4 carrier | 301 (31) | 25 (25.8) | 58 (32.4) | 0.5 |
| Family history of dementia | 279 (25.2) | 21 (19.1) | 51 (26) | 0.34 |
| Physical activity ≥300 units | 552 (49) | 44 (39.3) | 101 (50) | 0.13 |
| Alcohol, drink/week | 3.1 (5.4) | 1.9 (3.1)† | 2.4 (4.3) | 0.006 |
| Diet Quality | 65 (13.4) | 61.2 (12.2)† | 63 (12.5) | 0.003 |
| Body mass index, kg/m2 | 23.9 (5) | 26.4 (7.1)† | 24.8 (5.7)† | <.001 |
| Current smoking | 308 (27.5) | 29 (26.1) | 47 (23.6) | 0.52 |
| Elevated blood pressure | 16 (1.4) | 8 (7.1)† | 11 (5.4)† | <.001 |
| Diabetes | 3 (0.3) | 0 (0) | 1 (0.5) | 0.72 |
| Dyslipidemia | 251 (22.5) | 22 (19.8) | 49 (24.4) | 0.65 |
| Obesity | 121 (10.8) | 23 (20.5)† | 32 (15.9) | 0.003 |
| Depression | 247 (23.8) | 29 (29.6) | 54 (28.9) | 0.19 |
| Age at first pregnancy, years | 24.1 (7.4) | 23 (6) | 23.5 (6.2) | 0.4 |
| Year 30 | ||||
| Age at year 30, years | 55.3 (3.6) | 55.1 (3.6) | 54.5 (3.8)† | 0.027 |
| Parity | 1.8 (1.3) | 2.3 (1.2)† | 2.4 (1.3)† | <.001 |
| Education, years | 15.2 (2.5) | 14.6 (2.5)† | 15 (2.4) | 0.047 |
| Body mass index, kg/m2 | 30.5 (7.6) | 33.9 (9.1)† | 32.5 (8.5)† | <.001 |
| Gestational diabetes | 87 (7.7) | 11 (9.8) | 38 (18.8)† | <.001 |
| Hypertension | 392 (34.8) | 64 (57.1)† | 99 (49)† | <.001 |
| Diabetes | 154 (13.8) | 18 (16.7) | 36 (17.9) | 0.26 |
| Obesity | 535 (47.6) | 69 (62.7)† | 111 (55) | 0.003 |
| Cardiovascular event | 27 (2.4) | 6 (5.4) | 8 (4) | 0.12 |
| Traumatic brain Injury | 149 (13.4) | 14 (12.7) | 32 (16.3) | 0.53 |
HDP = Hypertensive disorders of pregnancy
p<0.05 in the post-hoc test using Bonferroni multiple comparisons (continuous variables) and unadjusted logistic regressions (categorical variables).