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. 2025 Jan 15;272(2):135. doi: 10.1007/s00415-024-12868-2

Table 3.

Results of cerebrospinal fluid analysis

Group 1 Group 2 p value
Mean SD Range N Mean SD Range N
CSF findings
 CSF white cell count (leucocytes/µl) 103.00 142.87 11–540 13 52.17 66.15 6–268 18 0.173
 CSF total protein (mg/l) 1.219 967 470–3710 11 865.06 475.83 407–1931 16 0.199
 CSF lysozyme (ng/ml) 4.25 0.35 3.9–4.6 2 3.07 1.80 1.5–6.9 7
 CSF neopterin (ng/ml) 5.20 1.78 2.5–6.9 4 4.66 4.10 2.1–15 14
 CSF sIL-2R (U/ml) nA nA nA 0 135.43 35.69 129–182 3
Laboratory findings
 Serum ACE (U/l) 151.00 74.00 77–225 2 79.53 11.28 70.2–98.6 4
 Serum lysozyme (mg/l) nA nA nA 0 30.05 16.13 18.2–73.9 10
 Serum neopterin (ng/ml) nA nA nA 0 3.94 1.70 2.8–7.3 5
 Serum sIL-2R (U/ml) 975.50 186.50 789–1162 2 1512.29 537.57 818–2433 7
 Serum calcium nA nA nA 0 nA nA nA 0

N = patients with elevation of the regarding parameter and exact value available; Upper limit of normal: CSF cell count 5/µl, CSF total protein > 400 mg/l, CSF lysozyme > 62 ng/ml, CSF neopterin > 1.5 ng/ml, CSF sIL-2R > 50 U/ml, serum ACE > 70 U/l, serum lysozyme > 17 mg/l, serum neopterin > 2,5 ng/ml, serum sIL-2R > 623 U/ml