Table-3.
Duodenum histological examinations.
| Parameter (μm) | Day | Control M (SD) | Probiotic M (SD) | p-value | d |
|---|---|---|---|---|---|
| Villi length | 1 d | 532 (127)a | 528 (116)a | 0.721 | NA |
| 7 d | 1142 (175)b | 1174 (168)b | 0.024 | 0.18 | |
| 14 d | 1523 (241)c | 1551 (206)c | 0.135 | NA | |
| 21 d | 1509 (206)c | 1583 (172)c | <0.001 | 0.39 | |
| 28 d | 1580 (222)d | 1697 (254)d | <0.001 | 0.49 | |
| 35 d | 1686 (207)e | 1758 (204)e | <0.001 | 0.35 | |
| p-value | <0.001 | <0.001 | |||
| Villi width | 1 d | 89 (20)a | 88 (19)a | 0.752 | NA |
| 7 d | 166 (37)b | 173 (37)b | 0.025 | 0.18 | |
| 14 d | 200 (42)c | 214 (45)c | <0.001 | 0.30 | |
| 21 d | 215 (46)d | 213 (42)c | 0.642 | NA | |
| 28 d | 229 (41)e | 240 (50)d | 0.002 | 0.25 | |
| 35 d | 246 (49)f | 246 (48)d | 0.888 | NA | |
| p-value | < 0.001 | < 0.001 | |||
| Crypt depth | 1 d | 74 (12)a | 76 (13)a | 0.152 | NA |
| 7 d | 143 (31)b | 148 (22)b | 0.031 | 0.18 | |
| 14 d | 190 (29)c | 185 (32)c | 0.078 | NA | |
| 21 d | 199 (27)d | 206 (31)d | 0.003 | 0.25 | |
| 28 d | 214 (34)e | 220 (33)e | 0.021 | 0.19 | |
| 35 d | 225 (39)e | 239 (43)f | <0.001 | 0.33 | |
| p-value | < 0.001 | < 0.001 | |||
| Muscle layer thickness | 1 d | 70 (20)a | 76 (20)a | <0.001 | 0.31 |
| 7 d | 116 (35)b | 120 (30)b | 0.187 | NA | |
| 14 d | 129 (37)c | 135 (39)c | 0.040 | 0.17 | |
| 21 d | 142 (36)d | 142 (33)d | 0.950 | NA | |
| 28 d | 157 (37)e | 163 (41)e | 0.065 | NA | |
| 35 d | 170 (55)f | 174 (47)f | 0.328 | NA | |
| p-value | < 0.001 | < 0.001 | |||
| Villi length/crypt depth | 1 d | 7.3 (2.1)a | 7.1 (1.7)a | 0.222 | NA |
| 7 d | 8.5 (4.3)b | 8.3 (3.8)b | 0.516 | NA | |
| 14 d | 8.2 (1.5)c | 8.5 (1.4)c | 0.002 | 0.26 | |
| 21 d | 7.7 (1.2)a | 7.8 (1.2)d | 0.185 | NA | |
| 28 d | 7.7 (4.2)a | 7.8 (1.5)d | 0.655 | NA | |
| 35 d | 8.1 (6.2)d | 8.1 (6.8)b | 0.901 | NA | |
| p-value | < 0.001 | < 0.001 |
M=Mean, SD=Standard deviation, d=Cohen’s d (effect size). Values with different superscript letters (a–e) in the same column are significantly different (p < 0.05)