Figure 1.

Lifespan extension by feeding PBA. Newly emerged adult flies were fed continuously on standard cornmeal/yeast/agar medium, with or without added PBA, and survival curves were measured. Each initial population was 400 flies. Data were combined from two separately run groups of 100 males plus two separately run groups of 100 virgin females. (a) w¹¹¹⁸ strain at 29°C. Ten millimolar PBA extends median survival by 33% (mean survival by 36%, maximum survival by 52%). (b) Canton-S wild type strain at 29°C. Five millimolar PBA extends median survival by 36% (mean survival by 40%, maximum by 41%). (c) w¹¹¹⁸ strain at 25°C. PBA is also effective at the lower temperature.