Table 3. Comparison of baseline characteristics and outcomes of patients between the AKI and non-AKI groups.
| Variables | Total (n=689) | AKI (n=201) | Non-AKI (n=488) | P values |
|---|---|---|---|---|
| Male | 417 (60.5) | 109 (54.2) | 308 (63.1) | 0.03* |
| Age (years) | 57.0 (48.0, 64.0) | 62.0 (54.0, 68.0) | 55.0 (46.0, 62.0) | <0.001* |
| Weight (kg) | 60.0 (53.0, 67.0) | 58.0 (52.0, 67.0) | 60.0 (53.0, 67.0) | 0.28 |
| Medical history | ||||
| Hypertension | 158 (22.9) | 71 (35.3) | 87 (17.8) | <0.001* |
| Diabetes mellitus | 62 (9.0) | 27 (13.4) | 35 (7.2) | 0.01* |
| Hyperlipidemia | 5 (0.7) | 1 (0.5) | 4 (0.8) | >0.99 |
| CAD | 12 (1.7) | 6 (3.0) | 6 (1.2) | 0.12 |
| CKD | 5 (0.7) | 3 (1.5) | 2 (0.4) | 0.15 |
| Nephrotoxic drugs | 33 (4.8) | 10 (5.0) | 23 (4.7) | >0.99 |
| Pre-op LVEF (%) | 63.0 (57.0, 67.0) | 63.0 (55.0, 67.0) | 63.0 (57.0, 67.0) | 0.56 |
| Pre-op examination | ||||
| Hemoglobin (g/L) | 134.0 (120.0, 145.0) | 129.0 (115.0, 139.0) | 136.0 (123.0, 146.0) | <0.001* |
| D-dimer (ng/mL) | 360.0 (240.0, 830.0) | 500.0 (290.0, 1,110.0) | 330.0 (220.0, 722.5) | <0.001* |
| Albumin (g/L) | 38.5 (36.3,40.9) | 37.7 (35.1, 40.1) | 38.8 (36.6, 41.3) | <0.001* |
| Baseline sCr (µmol/L) | 78.0 (65.3, 93.6) | 77.6 (63.2, 97.3) | 78.5 (66.8, 92.7) | 0.65 |
| Outcomes | ||||
| Hospital costs (10k CNY) | 14.8 (11.8, 19.4) | 19.7 (15.7, 26.3) | 13.5 (10.8, 16.9) | <0.001* |
| In-hospital mortality | 20 (2.9) | 15 (7.5) | 5 (1.0) | <0.001* |
| IABP | 43 (6.2) | 27 (13.4) | 16 (3.3) | <0.001* |
| CRRT | 19 (2.8) | 15 (7.5) | 4 (0.8) | <0.001* |
| ECMO | 11 (1.6) | 6 (3.0) | 5 (1.0) | 0.09 |
| MV (h) | 20.0 (13.0, 43.0) | 43.0 (19.0, 100.0) | 17.0 (10.8, 24.0) | <0.001* |
| ICU LOS (h) | 45.0 (27.0, 112.0) | 110.0 (46.0, 208.0) | 42.0 (22.0, 68.2) | <0.001* |
| AKI staging | ||||
| Stage 1 | 132 (65.7) | |||
| Stage 2 | 48 (23.9) | |||
| Stage 3 | 21 (10.4) |
Data were presented as median (interquartile range) or n (%). *, there is a statistical difference. AKI, acute kidney injury; CAD, coronary artery disease; CKD, chronic kidney disease; Nephrotoxic drugs, including immunosuppressants, angiotensin-converting enzyme inhibitors, angiotensin receptor blockers, non-steroidal anti-inflammatory drugs, antibiotics (including vancomycin, acyclovir, amphotericin B, aminoglycosides), mannitol, angiography agents, etc.; Pre-op, preoperative; LVEF, left ventricular ejection fraction; sCr, serum creatinine; CNY, Chinese yuan; IABP, intra-aortic balloon pump; CRRT, continuous renal replacement therapy; ECMO, extracorporeal membrane oxygenation; MV, mechanical ventilation; ICU LOS, intensive care unit length of stay.