Table 2.
Association of Mg and Ca concentrations with abnormal HbA1c for all participants
| Variables | Quartiles by Mg and Ca |
|||
|---|---|---|---|---|
| Q1 | Q2 | Q3 | Q4 | |
| Mg | ||||
| Mean (SD) | 0.77 ± 0.04 | 0.83 ± 0.01 | 0.88 ± 0.01 | 0.97 ± 0.12 |
| Case/N | 911/2829 | 776/3312 | 570/2729 | 632/3064 |
| OR (95%CI) | ||||
| Model 1† | 1 | 0.64 (0.57, 0.71)** | 0.55 (0.48, 0.62)** | 0.53 (0.47, 0.60)** |
| Model 2‡ | 1 | 0.70 (0.61, 0.81)** | 0.65 (0.56, 0.75)** | 0.61 (0.53, 0.71)** |
| Ca | ||||
| Mean (SD) | 2.13 ± 0.08 | 2.24 ± 0.02 | 2.31 ± 0.02 | 2.41 ± 0.07 |
| Case/N | 325/1146 | 288/1183 | 286/1171 | 312/1106 |
| OR (95%CI) | ||||
| Model 1† | 1 | 0.84 (0.70, 1.01) | 0.85 (0.71, 1.03) | 1.06 (0.88, 1.28) |
| Model 2‡ | 1 | 0.88 (0.70, 1.10) | 0.90 (0.72, 1.13) | 1.15 (0.92, 1.44) |
| Mg/Ca ratio | ||||
| Mean (SD) | 0.33 ± 0.02 | 0.37 ± 0.01 | 0.39 ± 0.01 | 0.44 ± 0.07 |
| Case/N | 378/1150 | 281/1152 | 264/1152 | 288/1152 |
| OR (95%CI) | ||||
| Model 1† | 1 | 0.64 (0.53, 0.77)** | 0.59 (0.49, 0.71)** | 0.64 (0.53, 0.77)** |
| Model 2‡ | 1 | 0.71 (0.57, 0.89)* | 0.63 (0.50, 0.78)** | 0.67 (0.54, 0.84)** |
Ca, calcium; Mg, Magnesium; OR, odd ratio; 95% CI, 95% confidence interval; Q, quartile; SD, standard deviation; HbA1c, glycosylated hemoglobin.
†
Model 1 adjusted for age and sex.
‡
Model 2 further adjusted for smoking status, BMI, alcohol consumption, hypotensor and hypoglycemic drug use.
*
p< 0.05
**
p< 0.001.