Figure 2. Expression of the Onconeural Antigens in Ri-PNS BCs Compared With Controls.
(A and C) Median boxplots of TPM expression of NOVA1 (A) and NOVA2 (C) in control luminal B BCs (left, light blue) vs Ri-PNS tumors (right, green). (B and D) Expression of the NOVA1 and NOVA2 protein in 10x magnification. Representative NOVA1 IHC staining in Ri-PNS BCs (top right corner) vs control tumors (top left corner). Representative NOVA2 IHC staining in Ri-PNS BCs (bottom right corner) vs control tumors (bottom left corner). Scale bars: 200 µm. BC = breast cancer; IHC = immunohistochemistry; PNS = paraneoplastic neurologic syndrome; TPM = transcripts per million.
