Table 4.

Results of the PpIX-TSLT measurements.

	Visit	All patients	Trajectory N=21	FDR-adjusted p value
				T0	T3	T5
mitoPO2 (mmHg)	T0	60.5 [47.8–78.0]; n=36	57.6 [50.0–68.8]	–	ns	ns
	T3	62.8 [47.9–76.1]; n=31	62.0 [47.9–73.2]	ns	–	ns
	T5	68.5 [58.8–91.3]; n=30	67.4 [57.8–91.7]	ns	ns	–
mitoVO2 (mmHg/s)	T0	3.8 [2.4–5.1]; n=36	3.6 [2.4–5.1]	–	ns	ns†
	T3	4.0 [2.9–4.7]; n=31	4.1 [2.6–4.7]	ns	–	ns
	T5	3.0 [2.3–4.4]; n=30	2.9 [2.1–3.8]	ns†	ns	–
mitoDO2 (mmHg/s)	T0	3.7 [2.4–5.9]; n=36	3.8 [2.7–6.3]	–	ns	ns
	T3	4.4 [3.2–6.9]; n=31	3.7 [3.0–7.1]	ns	–	ns
	T5	4.4 [3.2–6.3]; n=30	4.5 [3.4–6.0]	ns	ns	–

All data in median [interquartile range]. The last columns show significant differences between time points (Wilcoxon signed-rank tests, false discovery rate adjusted p values <0.05) in the trajectory sample with available data for all study visits.

mitoPO₂, mitochondrial oxygen tension; mitoVO₂, mitochondrial oxygen consumption; mitoDO₂, mitochondrial oxygen delivery; PpIX-TSLT, Protoporphyrin IX-Triplet State Lifetime Technique; T0, preoperative; T3, 6 ± 1 months; T5, 12 ± 1 months after laparoscopic sleeve gastrectomy.

^† p < 0.05 before false discovery rate adjustment; n.s., false discovery rate adjusted p value ≥ 0.05.