Table 3.
REV7 predicts outcomes In various cancers.
| Cancer Type | Prognostic Indicator | Reference |
|---|---|---|
| Triple negative breast | High REV7 expression is associated with shorter overall survival | (157) |
| Diffuse large B-cell lymphoma | High REV7 expression is associated with shorter progression-free survival and overall survival in patients treated with rituximab | (158) |
| Gastric | High REV7 expression is associated with shorter overall survival | (157) |
| Lung | High REV7 expression is associated with shorter overall survival | (157) |
| Melanoma | High REV7 expression is associated with increased tumor thickness | (159) |
| Ovarian | High REV7 expression is associated with shorter overall survival | (182) |
| Ovarian clear cell carcinoma | High REV7 expression is associated with shorter progression-free survival in advanced disease | (181) |
| Pancreatic ductal adenocarcinoma | High REV7 expression is associated with shorter overall survival in unresectable PDAC treated with platinum-based chemotherapy | (160) |
| Testicular germ cell | High REV7 expression is associated with chemotherapeutic resistance and shorter overall survival | (161, 162) |