Table A1.

MEDLINE search term via OVID for the PICO questions

PICO question #6	PICO question #7	PICO question #8	PICO question #9	PICO question #10	PICO question #11
exp Tooth Diseases/ exp Dental Caries/ caries.mp. dental caries.mp. carious lesion*.mp. tooth Decay.mp. dental Cavit*.mp. Cavit*.mp. demineralization*.mp. 1 or 2 or 3 or 4 or 5 or 6 or 7 or 8 or Dental Cavity Preparation/ caries excavat*.mp. caries remov*.mp. residual caries.mp. 11 or 12 or 13 or 14 Randomized Controlled Trials as Topic/ exp Controlled Clinical Trial/ RCT*.mp. randomized controlled Trial*.mp. randomised controlled Trial*.mp. systematic review*.mp. meta Analysis.mp. controlled clinical Trial.mp. randomized.mp. randomised.mp. controlled clinical Trial*.mp. cct*.mp. 16 or 17 or 18 or 19 or 20 or 21 or 22 or 23 or 24 or 25 or 26 or 27 10 and 15 and 28 limit 29 to (yr=”1990 -Current” and (english or french or german or russian))	exp dental restoration failure/ or exp dental restoration, permanent/ or exp dental restoration repair/ or dental marginal adaptation/ or exp diagnosis, oral/ exp Composite Resins/ dental restoration*.mp. filling*.mp. restoration*.mp. composit*.mp. 1 or 2 or 3 or 4 or 5 or 6 Rubber dams/ ((rubber adj dam*) or (oral adj dam*) or (dental adj dam*) or (latex adj dam*) or Kofferdam).mp. (“Optra Dam” or “OptraDam Plus” or OptiDam or FlexiDam or “Hygenic Fiesta”).mp. operatory field isolation.mp. 8 or 9 or 10 or 11 Randomized Controlled Trials as Topic/ exp Controlled Clinical Trial/ RCT*.mp. randomized controlled Trial*.mp. randomised controlled Trial*.mp. systematic review*.mp. meta Analysis.mp. controlled clinical Trial.mp. randomized.mp. randomised.mp. controlled clinical Trial*.mp. cct*.mp. 13 or 14 or 15 or 16 or 17 or 18 or 19 or 20 or 21 or 22 or 23 or 24 7 and 12 and 25 limit 26 to (yr=”1990 -Current” and (english or french or german or russian))	exp dental restoration failure/ or exp dental restoration, permanent/ or exp dental restoration repair/ or dental marginal adaptation/ or exp diagnosis, oral/ dental restoration*.mp. exp Composite Resins/ filling*.mp. restoration*.mp. composit*.mp. 1 or 2 or 3 or 4 or 5 or 6 (matrix adj1 system*).mp. (matrix adj1 band*).mp. matrice*.mp. (separation adj1 ring*).mp. (proximal adj1 contact*).mp. 8 or 9 or 10 or 11 or 12 exp dentistry/ 7 and 13 and 14 limit 15 to (yr=”1990-Current” and (english or french or german or russian))	exp dental restoration failure/ or exp dental restoration, permanent/ or exp dental restoration repair/ or dental marginal adaptation/ or exp diagnosis, oral/ exp Composite Resins dental restoration*.mp filling*.mp. restoration*.mp. composit*.mp. 1 or 2 or 3 or 4 or 5 or 6 Adhesives/ or Dentin-Bonding Agents/ Dental Bonding/ Acid Etching Dental/ Dental Etching/ bonding.mp. (adhes* adj1 system*).mp. adhesive.mp. 8 or 9 or 10 or 11 or 12 or 13 or 14 Randomized Controlled Trials as Topic/ exp Controlled Clinical Trial/ RCT*.mp. randomized controlled Trial*.mp. randomised controlled Trial*.mp. systematic review*.mp. meta Analysis.mp. controlled clinical Trial.mp. randomized.mp. randomised.mp. controlled clinical Trial*.mp. cct*.mp. 16 or 17 or 18 or 19 or 20 or 21 or 22 or 23 or 24 or 25 or 26 or 27 7 and 15 and 28 limit 29 to (yr=”1990 -Current” and (english or french or german or russian))	exp dental restoration failure/ or exp dental restoration, permanent/ or exp dental restoration repair/ or dental marginal adaptation/ or exp diagnosis, oral/ exp Composite Resins/ dental restoration*.mp. filling*.mp. restoration*.mp. composit*.mp. 1 or 2 or 3 or 4 or 5 or 6 Curing Light, Dental/ or “Light-Curing of Dental Adhesives”/ or Polymerization/ light cur*.mp. polymeri*ation.mp. curing protocol.mp. 3s PowerCure.mp. dual cur*.mp. 8 or 9 or 10 or 11 or 12 or 13 Randomized Controlled Trials as Topic/ exp Controlled Clinical Trial/ RCT*.mp. randomized controlled Trial*.mp. randomised controlled Trial*.mp. systematic review*.mp. meta Analysis.mp. controlled clinical Trial.mp. randomized.mp. randomised.mp. controlled clinical Trial*.mp. cct*.mp. 15 or 16 or 17 or 18 or 19 or 20 or 21 or 22 or 23 or 24 or 25 or 26 7 and 14 and 27 limit 28 to (yr=”1990 -Current” and (english or french or german or russian))	exp dental restoration failure/ or exp dental restoration, permanent/ or exp dental restoration repair/ or dental marginal adaptation/ exp Composite Resins/ dental restoration*.mp. filling*.mp. restoration*.mp. composit*.mp. 1 or 2 or 3 or 4 or 5 or 6 finishing.mp. polishing.mp. contouring.mp. 8 or 9 or 10 Randomized Controlled Trials as Topic/ exp Controlled Clinical Trial/ RCT*.mp. randomi*ed controlled Trial*.mp. systematic review*.mp. meta Analysis.mp. controlled clinical Trial.mp. randomi*ed.mp. controlled clinical Trial*.mp. cct*.mp. 12 or 13 or 14 or 15 or 16 or 17 or 18 or 19 or 20 or 21 7 and 11 and 22 limit 23 to (yr=”1990 -Current” and (english or french or german or russian))