Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2005 Jul 7;33(12):3733–3742. doi: 10.1093/nar/gki686

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author 2005. Published by Oxford University Press. All rights reserved

The online version of this article has been published under an open access model. Users are entitled to use, reproduce, disseminate, or display the open access version of this article for non-commercial purposes provided that: the original authorship is properly and fully attributed; the Journal and Oxford University Press are attributed as the original place of publication with the correct citation details given; if an article is subsequently reproduced or disseminated not in its entirety but only in part or as a derivative work this must be clearly indicated. For commercial re-use, please contact journals.permissions@oupjournals.org

PMC Copyright notice

Eye sections of control and treated rd1 mice at PN28 and photoreceptor cell numbers in the outer nuclear layer (ONL). Hematoxylin–eosin stained sections of eyes of (A) untreated, (B) PBS-treated, (C) 25-PS-PDEas ON-treated and (D) 25-LNA-PDEas ON-treated rd1 mice. A and B are representative of the entire ONL of the corresponding retinas, whereas (C and D) are selected are as showing markedly increased cell numbers in the ONL of ON-treated rd1 mice. Scale bars: 100 μm. (E) Counting of cells in the ONL showed a modest but significant overall increase of cells in 25-PS-PDEas or 25-LNA-PDEas ON-treated compared to PBS-treated eyes (P < 0.0001) or untreated eyes (P < 0.0001) (asterisk). Results were expressed as means ± SD, represented as vertical bars, and compared using the non-parametric Mann–Whitney test.