Table 3.
Marker | Allele | Allele frequency | Number of informative families | Z score | P |
Additive model: biallelic test | |||||
D5S1953 | 2 | 0.45 | 54 | 0.57 | 0.569 |
rs26307 | C | 0.81 | 35 | 1.73 | 0.084 |
rs27356 | C | 0.80 | 39 | 2.54 | 0.011* |
3088132 | G | 0.79 | 28 | 1.28 | 0.198 |
rs153929 | A | 0.76 | 48 | 1.61 | 0.107 |
rs258215 | A | 0.59 | 43 | 1.58 | 0.113 |
rs28006 | C | 0.74 | 34 | 1.62 | 0.104 |
rs25957 | C | 0.76 | 36 | 2.02 | 0.043* |
ANKH-OR | 1 | 0.47 | 59 | 1.62 | 0.105 |
D5S1991 | 2 | 0.48 | 58 | 1.33 | 0.181 |
D5S1954 | 1 | 0.64 | 54 | 0.65 | 0.515 |
Recessive model: biallelic test | |||||
D5S1953 | 2 | 0.43 | 48 | 0.45 | 0.683 |
rs26307 | C | 0.80 | 40 | 1.49 | 0.137 |
rs27356 | C | 0.79 | 44 | 2.32 | 0.020* |
3088132 | G | 0.79 | 31 | 1.19 | 0.233 |
rs153929 | A | 0.76 | 50 | 1.86 | 0.062 |
rs258215 | A | 0.58 | 32 | 1.55 | 0.120 |
rs28006 | C | 0.74 | 37 | 1.46 | 0.142 |
rs25957 | C | 0.76 | 38 | 1.65 | 0.098 |
ANKH-OR | 2 | 0.52 | 37 | -2.20 | 0.027* |
D5S1991 | 1 | 0.52 | 45 | -1.96 | 0.050* |
D5S1954 | 1 | 0.64 | 54 | 0.65 | 0.517 |
*Statistically significant findings. FBAT, family-based association testing.