Table 4.
FBAT-e analyses using setafftrait 0 -1 0, testing specifically for affected women
Marker | Allele | Allele frequency | Number of informative families | Z score | P |
Additive model: biallelic test | |||||
D5S1953 | 1 | 0.56 | 47 | 0.47 | 0.635 |
rs26307 | T | 0.19 | 22 | 0.32 | 0.751 |
rs27356 | T | 0.20 | 24 | 1.03 | 0.302 |
3088132 | C | 0.21 | 20 | 0.37 | 0.712 |
rs153929 | G | 0.24 | 46 | 1.31 | 0.191 |
rs258215 | T | 0.41 | 30 | 1.54 | 0.123 |
rs28006 | T | 0.26 | 31 | 2.82 | 0.004* |
rs25957 | G | 0.23 | 23 | 2.82 | 0.004* |
ANKH-OR | 2 | 0.52 | 59 | 0.94 | 0.347 |
D5S1991 | 1 | 0.52 | 53 | 1.10 | 0.270 |
D5S1954 | 2 | 0.36 | 45 | 1.38 | 0.168 |
Recessive model: biallelic test | |||||
D5S1953 | 2 | 0.44 | 39 | -1.21 | 0.227 |
rs26307 | C | 0.81 | 26 | 0.52 | 0.606 |
rs27356 | T | 0.20 | 10 | 1.81 | 0.069 |
3088132 | G | 0.79 | 22 | 0.08 | 0.930 |
rs153929 | A | 0.76 | 44 | -1.39 | 0.162 |
rs258215 | A | 0.58 | 21 | -1.76 | 0.077 |
rs28006 | C | 0.74 | 28 | -2.49 | 0.012* |
rs25957 | C | 0.76 | 23 | -2.25 | 0.024* |
ANKH-OR | 2 | 0.52 | 34 | 1.14 | 0.254 |
D5S1991 | 1 | 0.51 | 33 | 1.52 | 0.127 |
D5S1954 | 1 | 0.64 | 45 | -1.54 | 0.122 |
*Statistically significant findings. FBAT, family-based association testing.