Table 5.
Marker | Allele | Allele frequency | Number of informative families | Z score | P |
Additive model: biallelic test | |||||
D5S1953 | 2 | 0.44 | 47 | 0.25 | 0.805 |
rs26307 | C | 0.80 | 22 | 2.06 | 0.039* |
rs27356 | C | 0.79 | 25 | 2.63 | 0.008* |
3088132 | G | 0.79 | 18 | 1.23 | 0.216 |
rs153929 | A | 0.76 | 36 | 0.49 | 0.619 |
rs258215 | A | 0.58 | 32 | 0.81 | 0.419 |
rs28006 | T | 0.26 | 37 | 0.15 | 0.877 |
rs25957 | C | 0.77 | 33 | 0.76 | 0.446 |
ANKH-OR | 1 | 0.48 | 64 | 1.04 | 0.297 |
D5S1991 | 2 | 0.49 | 64 | 0.39 | 0.696 |
D5S1954 | 2 | 0.36 | 49 | 0.33 | 0.736 |
Recessive model: biallelic test | |||||
D5S1953 | 1 | 0.56 | 40 | -0.83 | 0.406 |
rs26307 | C | 0.81 | 25 | 2.51 | 0.012* |
rs27356 | C | 0.80 | 28 | 2.99 | 0.002* |
3088132 | G | 0.79 | 22 | 1.44 | 0.149 |
rs153929 | A | 0.76 | 39 | 0.71 | 0.477 |
rs258215 | A | 0.59 | 23 | 0.60 | 0.543 |
rs28006 | T | 0.26 | 16 | 0.33 | 0.739 |
rs25957 | C | 0.76 | 29 | 0.64 | 0.518 |
ANKH-OR | 2 | 0.52 | 44 | -1.26 | 0.205 |
D5S1991 | 1 | 0.51 | 46 | -0.71 | 0.472 |
D5S1954 | 1 | 0.64 | 43 | -0.65 | 0.510 |
*Statistically significant findings. FBAT, family-based association testing.